The thesis aims to demonstrate that metal organic frameworks (MOFs) are effective platforms for inhibition of microbial growth. The research will focus on fabrication of zinc and copper MOFs by solvothermal wet-chemistry, crystallization, characterization by microscopy and spectroscopy and evaluation with E. coli (Escherichia coli) found in drinking water by using optical density assay. We anticipate these MOFs will be extremely potent, since iron (III), nickel, copper and cobalt have intrinsic antibacterial activity. The current published Zn MOFs research focus is on fabricated for gas storage matrices or catalysis or separation and not self-sterilization coatings. Other research problems to be addressed are the relationship between metal connectivity and ligand-based luminescence, MOF stability in an aqueous environment, recycling and coating persistence. The merits of this research are to design potent disinfectants that can also be used as coating to keep surfaces sterile.
September 29, 2014
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